在骨骨折手术后的术后败血症和败血性休克
Christian A Gonzalez1, Alana O'Mara2, Jacquelyn P Cruz3
1University of Nevada, Reno School of Medicine, Reno, NV, USA.
Injury
|June 26, 2023
概括
败血症和败血性休克分别影响1.0%和0.6%的关节骨折患者. 在部骨折手术中早期发现和治疗败血症对于降低高死亡率至关重要.
科学领域:
- 老年人手术是一门老年手术.
- 传染病流行病学 传染病流行病学
- 关键护理医学 关键护理医学
背景情况:
- 有限的研究存在于骨骨折患者的败血症和败血性休克率.
- 关节骨折患者表现出明显的临床和预后形状对于败血症和败血性休克.
研究的目的:
- 确定骨骨折手术患者中败血症和败血性休克的发生率.
- 确定与败血症和败血症休克相关的风险因素和死亡率.
- 评估在这个人群中发生败血症或败血性休克之前的常见感染原因.
主要方法:
- 使用美国外科医生学院国家外科质量改进计划 (ACS-NSQIP) 数据库从2015-2019年.
- 采用多变量回归模型来识别风险因素和评估30天死亡率.
- 在分析中控制了手术前变量和并发症.
主要成果:
- 在86,438名关节骨折患者中发生了败血症 (1.0%) 和败血性休克 (0.6%).
- 危险因素包括男性性别,糖尿病,慢性肺炎,功能依赖,高ASA类,贫血和低albuminemia.
- 与无菌患者 (4.8%) 相比,败血症 (16.2%) 和败血性休克 (40.8%) 的30天死亡率明显高.
结论:
- 败血症和败血性休克的发病率分别为1.0%和0.6%的部骨折手术后.
- 贫血和低albuminemia是两个条件的潜在可修改的危险因素.
- 尿路感染,肺炎和手术部位感染是主要的先发性感染,强调了预防和早期治疗的必要性.
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