禁烟后血清空腹葡萄糖变化的关联与预测脂肪肝得分的变化
Saemi Han1, Seogsong Jeong2,3, Joseph C Ahn4
1Department of Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Scientific reports
|June 26, 2023
概括
戒烟后禁食血清葡萄糖 (FSG) 升高与脂肪肝疾病的风险更高有关. 对前吸烟者来说,监测FSG和管理心血管因素至关重要.
科学领域:
- 代谢健康 代谢健康
- 肝病学 肝病学是一种肝病学.
- 戒烟的研究 戒烟的研究
背景情况:
- 戒烟往往会导致代谢变化,包括体重增加和高血糖症.
- 禁食血清葡萄糖 (FSG) 停止后的变化与患脂肪肝疾病的风险之间的关系尚不清楚.
研究的目的:
- 调查FSG水平停止后变化与非酒精性脂肪肝疾病 (NAFLD) 风险之间的关联.
- 评估戒烟后FSG波动对NAFLD风险的影响.
主要方法:
- 分析了111,106名40岁以上的韩国成年人至少两次健康检查的数据.
- 使用韩国国家健康和营养检查调查的非酒精性脂肪肝病 (K-NAFLD) 评分评估脂肪肝状况.
- 应用线性和逻辑回归模型来确定调整的平均值 (aMean) 和几率比率 (aOR) 以95%的置信区间.
主要成果:
- 与稳定或下降的FSG水平相比,高FSG停止后 (a平均1.28) 与更高的K-NAFLD得分相关.
- 与FSG水平升高的参与者相比,在FSG水平稳定 (aOR 0.38) 或下降 (aOR 0.17) 的参与者中,脂肪肝的风险明显较低.
结论:
- 停产后FSG的升高是发展NAFLD的重要危险因素.
- 经历FSG增加的前吸烟者可能受益于有针对性的血糖水平监测和心血管风险因素的综合管理.
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