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Updated: Jul 25, 2025

In Vitro Establishment of a Genetically Engineered Murine Head and Neck Cancer Cell Line using an Adeno-Associated Virus-Cas9 System
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人类乳头瘤病毒的整合转化染色质以驱动瘤发生

Mehran Karimzadeh1,2,3, Christopher Arlidge2, Ariana Rostami1,2

  • 1Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

Genome biology
|June 26, 2023
PubMed
概括

人类乳头瘤病毒 (HPV) 集成可以改变宿主细胞染色质,调节必要的基因并促进癌症的发展. 这项研究揭示了HPV驱动瘤发生的新机制.

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