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相关概念视频

Allergic Reactions02:06

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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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儿科实践中的过敏接触性皮肤炎.

Kam Lun Hon1, Alexander K C Leung2, James W C H Cheng3

  • 1Department of Paediatrics, CUHKMC, The Chinese University of Hong Kong, Hong Kong, China.

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概括

过敏性接触性皮肤炎 (ACD) 严重影响儿童和年轻人,造成生活质量问题. 通过病史,检查和补丁测试进行早期诊断,结合避免过敏原和适当的皮质类固醇治疗,是管理这种常见疾病的关键.

关键词:
过敏原是一种过敏原.过敏接触性皮肤炎过敏接触性皮肤炎这是一种沉重的疾病.生活质量生活质量.补丁测试 补丁测试 补丁测试第四类推迟过敏症.

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科学领域:

  • 皮肤病学 皮肤病学
  • 儿科 儿科 儿科
  • 免疫学 免疫学 免疫学

背景情况:

  • 过敏性接触性皮肤炎 (ACD) 是一种广泛的皮肤疾病,影响儿童,青少年和年轻人.
  • 患有ACD的患者经历了显著的心理社会和生活质量 (QoL) 挑战,这给孩子和他们的照顾者带来了负担.
  • ACD代表了一种普遍的免疫毒性形式,具有相当大的公共卫生影响.

研究的目的:

  • 提供对过敏性接触性皮肤炎 (ACD) 的全面概述.
  • 讨论ACD的常见和不太常见的原因.
  • 审查目前儿童群体中ACD的诊断和管理策略.

主要方法:

  • 使用PubMed临床查询进行了广泛的文献审查.
  • 关键词"过敏性接触性皮肤炎"在2022年8月使用,重点是关于儿童的英语文学.
  • 包括的研究类型包括元分析,RCT,临床试验,观察性研究,指导方针和病例报告.

主要成果:

  • ACD影响超过20%的儿童和成年人,导致显著的 QoL 损害.
  • 症状包括,囊泡和红斑;治疗包括局部或全身皮质类固醇.
  • 当初始治疗失败或诊断不确定时,建议进行贴片测试.

结论:

  • ACD是一种常见的,沉重的疾病,具有身体,心理和经济影响.
  • 诊断依赖于患者病史,体检和潜在的皮肤贴片测试来识别过敏原.
  • 管理中心关于避免过敏原和适当使用局部或全身皮质类固醇.