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Updated: Jul 25, 2025

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

Published on: December 16, 2021

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Zfp362通过限制Treg细胞功能而不是促进Th17细胞分化来增强小鼠结肠炎症

Susanne Herppich1, Lisa Hoenicke1, Fabian Kern2,3

  • 1Department Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

European journal of immunology
|June 27, 2023
PubMed
概括

指蛋白362 (Zfp362) 抑制调节性T细胞 (Treg) 功能,影响结肠炎症. 它的缺失增加了Treg细胞,减少了炎症的严重程度,而不是影响T辅助17 (Th17) 细胞的分化.

关键词:
肠道免疫 肠道免疫粘膜炎症是一种粘膜炎症.Th17 这是一个很好的方法.在Treg细胞中.Zfp3622 这是一本书.

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