地中海饮食与多发性硬化症风险之间的反向关联
Lars Alfredsson1, Tomas Olsson2, Anna Karin Hedström3
1Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden/Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden.
概括
坚持地中海饮食可以降低患多发性硬化症 (MS) 的风险. 这种饮食模式在最近的一项基于人口的研究中显示,与西方风格的饮食相比,这种饮食模式具有保护作用.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 营养科学 营养科学
背景情况:
- 饮食模式越来越多地与炎症性疾病的发病有关.
- 了解饮食在多发性硬化症 (MS) 风险中的作用对于预防策略至关重要.
研究的目的:
- 调查饮食习惯与患多发性硬化症 (MS) 的风险之间的联系.
主要方法:
- 一项基于人口的病例控制研究,涉及1953例多发性硬化症病例和3557例对照.
- 评估了诊断前5年的饮食习惯.
- 后勤回归模型用于计算调整的赔率比率 (OR) 和95%置信区间 (CI),控制环境和生活方式因素.
主要成果:
- 与西式饮食相比,地中海饮食与MS的风险明显降低 (调整后OR=0.54,95%CI:0.34-0.86).
- 在素食/素食饮食或低血糖指数饮食与MS风险之间没有发现显著的关联.
结论:
- 地中海饮食可能有保护作用,防止多发性硬化症的发展.
- 对预防多发性硬化症的饮食干预措施的进一步研究是有必要的.
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