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多面性碳点:朝着对pH的响应提供5-甲,用于体外抗增殖活性

Navpreet Kaur1, Pranav Tiwari2, Pawan Kumar3

  • 1Discipline of Biosciences and Bio-Medical Engineering, Indian Institute of Technology Indore, Simrol, Khandwa Road, Indore 453552, India.

ACS applied bio materials
|June 27, 2023
PubMed
概括

研究人员开发了化碳点 (N@PEGCDs),用于联合诊断和治疗. 这些生物相容纳米颗粒有效携带5-甲 (5-FU),显示向癌细胞毒性和潜在的先进的药物输送系统.

关键词:
5 - - 甲酸是一种5甲.这是一种抗癌药物.生物相容性的生物相容性碳点是指碳点的部分.药物输送是药物输送的过程.的兴奋剂的兴奋剂.

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...