在非常老年患者中快速管理一次性甲状腺淋巴瘤
Pierre Yves Marcy1, Frederic Bauduer2, Juliette Thariat3
1Radiodiagnostics and Interventional Radiology Department, Polyclinics ELSAN Medipole Sud, Quartier Quiez, 83189 Ollioules, France.
Current oncology (Toronto, Ont.)
|June 27, 2023
概括
在甲状腺中,一种罕见的胃马尔托马转化为扩散性大B细胞淋巴瘤 (DLBCL) 的病例,使用超声导向的核心针活检来诊断. 这种侵袭性淋巴瘤表现出压缩性部症状,突出了快速诊断和量身定制治疗的必要性.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 放射学 放射学是一门学科.
背景情况:
- 甲状腺恶性瘤可以呈现为快速增长的宫质量,有时与压缩部症状相关.
- 这位患者有哈希莫托甲状腺炎的病史和之前的胃马尔托马切除.
- 准确和及时的组织学诊断对于有效管理侵袭性甲状腺疾病至关重要.
研究的目的:
- 报告一种极为罕见的胃马尔托马转变为甲状腺中扩散性大B细胞淋巴瘤 (DLBCL) 的病例.
- 强调超声导向核心针活检在快速诊断和管理中的实用性.
- 讨论原始恶性甲状腺淋巴瘤的临床表现,诊断过程和治疗挑战.
主要方法:
- 超声波 (美国) 图像识别出一个大的低音性甲状腺质量.
- 进行了皮肤穿透的间歇性美国指导的18G核心针活检 (CNB) 以进行组织学诊断.
- FDG PET成像评估了疾病的程度,并确定了多焦点疾病.
主要成果:
- 中央银行证实甲状腺的大型B细胞淋巴瘤 (DLBCL) 的扩散.
- FDG PET显示出明显的甲状腺和胃焦点,表明传播疾病 (第三阶段).
- 一个预后名录显示,一年的整体存活率为52%.
结论:
- 超声导向的CNB促进了迅速诊断和针对性地管理侵袭性甲状腺淋巴瘤.
- 马尔托马在胃部和甲状腺部位转化为DLBCL非常罕见.
- 尽管迅速启动了R-CVP化疗,但患者的预后仍然很差,这凸显了疾病的攻击性.
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