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使用Yb₂O₃.CuO@rGO纳米复合材料用于在真实样本中灵敏检测 Askorbic 酸

Jahir Ahmed^1,2, Mohd Faisal^1,2, Jari S Algethami^1,2

¹Promising Centre for Sensors and Electronic Devices (PCSED), Advanced Materials and Nano-Research Centre, Najran University, Najran 11001, Saudi Arabia.

|June 27, 2023

概括

使用Yb2O3.CuO@rGO纳米复合材料的新型电化学传感器有效检测酸 (AA),这是一个关键的氧化应激生物标志物. 这种可靠的传感器在血液血清和维生素C片中显示出高灵敏度和选择性AA检测.

科学领域:

电化学电化学电化学
材料科学材料科学材料科学
生物医学传感传感器

背景情况:

亚酸 (AA) 是一种重要的抗氧化剂,也是氧化应激的潜在生物标志物.
对AA的敏感和选择性检测对于临床诊断至关重要.
新型纳米材料的开发可以提高电化学传感器的性能.

研究的目的:

设计一个敏感和选择性的电化学传感器,用于检测酸 (AA).
为传感器开发使用一种新的Yb2O3.CuO@rGO纳米复合材料.
评估传感器在现实世界样本中检测AA的性能.

主要方法:

用Yb2O3.CuO@rGO纳米复合材料修改一个玻璃碳电极 (GCE).
纳米复合材料的电化学表征和传感器性能评估.
在酸盐缓冲区,人体血清和维生素C片中检测AA.

主要成果:

对于AA,Yb2O3.CuO@rGO/GCE传感器表现出高灵敏度 (0.4341μAμM-1cm-2) 和低检测极限 (0.062μM).
传感器展示了广泛的检测范围 (0.51571μM) 和出色的选择性.
在人血清和维生素C片中确切地确定了AA,具有良好的可重复性,可重复性和稳定性.

结论:

开发的Yb2O3.CuO@rGO/GCE传感器是一个高度敏感和选择性的AA检测平台.
传感器显示出在生物和制药样品中可靠量化AA的巨大潜力.
这项工作有助于推进用于氧化应激监测的电化学生物传感.

关键词:

Yb2O3.CuO@rGO 的时间电压计传感器是指电压计传感器.亚斯科布酸是什么亚斯科布酸人类血液血清的人类血清维生素C是维生素C的重要组成部分.

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