功能性生物材料用于局部控制正统牙牙运动
Yi Lin1, Moyu Lara Fu2, Ingrid Harb3
1Division of Orthodontics, Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, CA 94143, USA.
Journal of functional biomaterials
|June 27, 2023
概括
生物材料可以通过影响骨重塑来改变正义牙运动 (OTM). 本综述探讨了加速或阻碍OTM的材料及其对骨移植的影响,以帮助治疗规划.
科学领域:
- 生物材料科学 生物材料科学
- 矯正牙科 矯正牙科是一種矯正牙科.
- 组织工程是组织工程.
背景情况:
- ортодонтика牙运动 (OTM) 涉及骨和牙周带重塑,由RANKL等信号因子调节.
- 生物材料和骨移植替代品用于膜骨缺陷,可以影响OTM.
- 了解这些相互作用对于优化正义牙科治疗持续时间和保留时间至关重要.
研究的目的:
- 审查调节OTM速度 (加速或阻碍) 的功能生物材料.
- 为了检查膜骨移植材料对OTM的影响.
- 总结这些生物材料的作用机制和潜在副作用.
主要方法:
- 对影响OTM的生物材料研究的文献综述.
- 在OTM过程中参与骨重塑的信号通路的分析.
- 评估与正义牙科治疗和骨移植一起使用的生物材料.
主要成果:
- 功能化生物材料可以通过调节骨重塑来增强或抑制OTM.
- 气膜骨移植材料可以改变当地的环境,影响OTM.
- 移植后OTM的最佳时间通常是8周,但需要进一步验证人类研究.
结论:
- 生物材料为控制OTM速度和改善结果提供了潜力.
- 需要进一步进行人体临床试验,以确认OTM中的生物材料的有效性和安全性.
- 仔细考虑生物材料的类型和时间对于成功的正义牙科治疗和骨再生至关重要.
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