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在刚性和灵活的真实动脉静脉囊中进行压力分析,在体外进行厚度变化

Jonhattan Ferreira Rangel¹, Willyam Brito de Almeida Santos², Thércio Henrique de Carvalho Costa²

¹Materials Science and Engineering Post-Graduation, Department of Materials Science and Engineering, Federal University of Rio Grande do Norte-UFRN, Natal 59078-970, Brazil.

Journal of functional biomaterials

|June 27, 2023

概括

一个1毫米灵活的动脉静脉 (AVF) 模型紧密地模仿生理压力并减少压力下降,为改善AVF替代品和患者生活质量提供了一个有希望的基础.

科学领域:

生物医学工程生物医学工程
流体动力学流体动力学
血管接入血管接入

背景情况:

动脉静脉 (AVF) 是血液透析的首选血管通道,但可能导致并发症.
了解AVF流体动力学对于缓解问题和改善患者结果至关重要.

研究的目的:

在刚性和灵活的AVF模型中分析压力变化.
根据患者特定的计算机断层扫描数据评估AVF模型.
为了确定最佳的AVF设计以减少并发症.

主要方法:

计算机断层扫描被用于从患者数据中获得AVF几何.
创建了AVF模型并适应了脉动式流量板.
实验室测试模拟了抽缩 - 放缩脉冲以测量压力变化.

主要成果:

与灵活模型相比,在刚性AVF模型中观察到更高的压力峰值.
一个1毫米的柔性AVF显示压力屈曲接近生理价值.
1毫米的柔性AVF表现出比刚性模型更小的压力下降.

结论:

1毫米灵活的AVF模型在压力动态方面表现出卓越的性能.
这种灵活的AVF设计显示出作为开发改进的AVF替代品的基础的潜力.
优化AVF结构可以带来更好的患者生活质量.

关键词:

动脉静脉状囊动脉静脉状囊灵活的灵活的灵活的灵活的压力脉冲脉冲的压力刚性刚性刚性的

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