一个倾向匹配的比较缺血性脑损伤在术后MRI在内血管与开放的动脉重建对比开放的动脉
Zsuzsanna Mihály1, Samuel Booth1, Dat Tin Nguyen2,3
1Department of Vascular and Endovascular Surgery, Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.
Journal of cardiovascular development and disease
|June 27, 2023
概括
在一项匹配的研究中,动脉支架 (CAS) 与动脉内关节切除术 (CEA) 相比,导致更频繁和更大的急性缺血性脑病变. 这些新的病变与神经症状没有相关性.
科学领域:
- 神经学 神经学
- 血管外科 血管外科
- 放射学 放射学是一门学科.
背景情况:
- 脑血管疾病的管理包括手术干预,如动脉内关节切除术 (CEA) 和动脉支架 (CAS).
- 在术后评估新的缺血性脑病变的发生率和数量对于患者的治疗结果至关重要.
研究的目的:
- 为了比较CEA和CAS后急性缺血性脑病变的数量和体积.
- 利用倾向匹配的设计来进行这些干预措施的稳健比较.
主要方法:
- 前性,单中心,匹配的病例控制研究.
- 在手术后12-48小时内进行CT血管造影 (CTA) 进行斑块分析和MRI进行病变评估.
- 倾向性得分匹配 (1:1比) 来控制混变量.
主要成果:
- 分析了21对匹配的患者对.
- 与CEA组相比,CAS组的急性缺血性脑病变发生率更高 (47.6%与14.2%) 和体积更大.
- 在新的缺血病变和神经症状之间没有发现关联.
结论:
- 动脉支架与新的急性缺血性脑病变的频率显著增加有关.
- 这些发现表明,CAS和CEA之间的血事件的程序风险可能存在差异.
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