根据放射性外观,区分由菌体引起的肺结节与由肺癌引起的肺结节
Michael W Peterson1,2, Ratnali Jain1, Kurt Hildebrandt3
1Fresno Department of Medicine, University of California (San Francisco), San Francisco, CA 93701, USA.
Journal of fungi (Basel, Switzerland)
|June 27, 2023
概括
放射性发现,如腔腔结节,卫星结节和慢性肺病,可以帮助区分菌性肺炎 (真菌性肺感染) 和肺癌. 这种差异化可以减少不必要的侵入性手术和患者的成本.
科学领域:
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 菌 (coccidioidomycosis) 是一种流行性真菌感染,导致肺结节,在CT扫描上往往无法与早期肺癌区分.
- 从肺癌中区分结相关的肺结节是具有挑战性的,经常导致侵入性和昂贵的诊断评估.
研究的目的:
- 在胸部CT扫描上识别放射性特征,可以区分由菌菌菌病引起的肺结节与由肺癌引起的肺结节.
主要方法:
- 对302名生物检测证明是菌瘤或支气管癌的患者的胸部CT扫描进行了回顾性审查.
- 两位经验丰富的放射科医生对诊断失明,评估了放射特征,以确定其诊断效用.
主要成果:
- 单变体和多变体分析确定了肺癌和菌感染之间的显著差异,包括年龄,结节直径,结节腔化,卫星结节和慢性肺病.
- 腔腔结节,卫星结节和慢性肺病在临床决策中表现出足够的歧视力.
结论:
- 评估特定的放射性发现 (腔腔结节,卫星结节,慢性肺病) 可以显著改善菌菌和肺癌之间的差异化.
- 这种方法可以减少对不必要的入侵性研究的需求,从而降低在特有地区的成本和患者风险.
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