诺基诺相关运动障碍:文献综述
Jamir Pitton Rissardo1, Ana Letícia Fornari Caprara1
1Medicine Department, Federal University of Santa Maria, Santa Maria 97105-900, Brazil.
Medicines (Basel, Switzerland)
|June 27, 2023
概括
诺基诺 (FQNs) 可以导致运动障碍 (MDs). 大多数患者在药物戒断和管理后完全康复,但对于FQN诱导的MDs需要长期随访.
科学领域:
- 神经学 神经学
- 药理学 药理学是指药理学的学科.
- 临床医学 临床医学
背景情况:
- 诺 (FQNs) 与中枢神经系统的副作用有关.
- 运动障碍 (MDs) 是已知的,尽管不常见的,FQNs的不良影响.
研究的目的:
- 审查FQN相关运动障碍的临床流行病学概况.
- 探索FQN诱导的MDs的病理生理机制和管理策略.
主要方法:
- 来自六个数据库 (1988-2022) 的报告的系统审查.
- 包括45份报告,详细介绍51例与FQN相关的MDs.
- 对患者人口统计学,FQN类型,MD类型,发病和康复的分析.
主要成果:
- 最常见的MDs是肌 (25例) 和动力障碍 (13例).
- 患者主要是男性 (54.16%),平均年龄为67岁.
- 超过95%的人在治疗后完全康复,其中80.95%的人在戒药一周内康复.
结论:
- FQNs可以诱导一系列的运动障碍,其中肌细胞瘤是最常见的.
- 迅速戒药和管理导致高康复率.
- 进一步的研究应侧重于长期随访,并结合FQN诱导的肌结核的电诊断研究.
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