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营养药作为对诱导损伤的替代方法:叙述性审查
Herbert Ryan Marini1, Federica Bellone1, Antonino Catalano1
1Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.
Metabolites
|June 27, 2023
概括
暴露会通过各种分子途径损害和骨,可能导致慢性病 (CKD). 地中海饮食中的营养药物可以提供一种安全的策略,用于管理引起的损伤,并预防CKD.
科学领域:
- 环境健康 环境健康
- 腎臟病學 (nephrology) 是一種醫學專業.
- 毒理学 毒理学 毒理学
背景情况:
- (Cd) 是一种不可生物降解的环境污染物,具有很长的生物半衰期,对公众健康构成重大风险.
- 脏是积和毒性的主要目标器官,导致形态和功能损伤.
- 暴露与骨脆弱性有关,由直接影响骨矿化和二次功能衰竭引起.
研究的目的:
- 审查关于诱导损伤机制的实验和临床数据.
- 评估目前对毒性的治疗策略.
- 探索营养药在管理引起的慢性病 (CKD) 中的作用.
主要方法:
- 实验和临床研究的叙述性综述.
- 分析涉及毒性的分子途径,包括脂质过氧化,炎症和亡.
- 调查肠道失调症,CKD和饮食因素之间的联系.
主要成果:
- 会通过复杂的分子交叉来诱导球体和管状损伤,从而导致CKD.
- 暴露的次要功能衰竭加剧了骨脆弱性.
- 改变肠道微生物群的组成和功能与CKD有关.
- 营养药物,特别是地中海饮食中的营养药物,在治疗Cd引起的损伤方面表现有前途.
结论:
- 的毒性会通过多个分子途径引发严重的损伤,导致CKD.
- 地中海饮食及其营养成分可以作为引起的毒性的一种安全的治疗方法.
- 针对肠道微生物群的饮食干预措施代表了预防和治疗CKD的潜在策略.
关键词:
在CKD中,它是最好的.地中海饮食 地中海饮食这是一个PTE.灭症 (apoptosis) 是一种死亡的过程.骨头 骨头 骨头 骨头和是最重要的元素.这是一种炎症炎症炎症炎症.脏 脏 脏是什么?我们的微生物群.营养保健品 营养保健品氧化应激是一种氧化应激.更多相关视频
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