纸质电化学生物传感器用于诊断病毒性疾病
Vanessa N Ataide1, Lauro A Pradela-Filho2, Wilson A Ameku2
1Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Av. Prof Lineu Prestes, 748, 05508-000, São Paulo, SP, Brazil. vanneiva@usp.br.
Mikrochimica acta
|June 27, 2023
概括
本次综述强调了用于检测包括COVID-19在内的各种病毒的电化学基于纸张的分析设备 (ePAD) 的最新进展. 这些低成本的便携式生物传感器在资源有限的环境中为分散的诊断提供了潜力.
科学领域:
- 分析化学 分析化学
- 生物传感器是一种生物传感器.
- 纳米技术 纳米技术
背景情况:
- 基于纸张的电化学分析设备 (ePAD) 是低成本,便携和一次性平台,越来越受欢迎.
- 电化学生物传感器为疾病诊断和分散分析提供了多功能平台.
- 纳米材料和微流体增强生物传感器的灵敏度和选择性.
研究的目的:
- 审查用于病毒检测的电化学纸质设备的最新发展.
- 讨论制造方法,设备设计和生物分子固定化策略.
- 为推进基于纸张的电化学生物传感器提出前景和挑战.
主要方法:
- 对用于病毒检测的ePAD最新文献的审查.
- 分析电极制造,设备设计和固定化技术.
- 讨论在检测COVID-19,登革热,寨卡,肝炎,埃博拉,艾滋病和流感等病毒中的应用.
主要成果:
- 在敏感和选择性病毒检测方面,ePAD显得有前途.
- 与微流体学的整合改善了分析物运输和传感器性能.
- 这些设备可以准影响全球健康的各种病毒.
结论:
- 基于纸张的电化学生物传感器是快速,分散的病毒诊断的宝贵工具.
- 克服当前的挑战对于广泛采用至关重要,特别是在资源有限的地区.
- 制造和固定化策略的持续研究将推动未来的进步.
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