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Updated: Jul 25, 2025

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怀孕状态与术后恶心和吐无关:一个匹配的病例对照研究

A Deljou¹, A Kanaparthi², J Soleimani²

¹Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine and Science, 200 First St SW, Rochester, MN, 55905, USA. deljou.atousa@mayo.edu.

Journal of anesthesia

|June 27, 2023

概括

在接受非产科手术的妇女中,怀孕不会增加术后恶心和吐 (PONV) 的风险. 然而,麻醉科医生在与非孕妇相比,对孕妇施用预防性反药的数量较少.

科学领域:

麻醉学和外科手术期间的医学.
产科和妇科产科和妇科

背景情况:

手术后恶心和吐 (PONV) 是全身麻醉后的常见并发症.
现有的研究经常分别检查孕妇和非孕妇的PONV,对比数据有限.
怀孕作为PONV风险因素及其管理仍未得到充分探索.

研究的目的:

为了比较孕妇PONV的发病率与接受非产科手术的非孕妇.
调查怀孕状态是否会影响患PONV的风险.
为了确定两组之间在PONV预防和治疗中的潜在差异.

主要方法:

采用了追溯病例控制队列研究设计.
根据年龄,手术年份和手术程序,237名孕妇与474名非孕妇进行了1:2匹配.
从电子医疗记录中提取的数据包括风险因素,抗使用,PONV发生率和住院细节. 使用了后勤和多项后勤回归分析.

主要成果:

在孕妇中,PONV的发病率为21.5%,非孕妇中为15.2%.
在怀孕状态和PONV风险之间没有发现统计学上显著的关联 (aOR1.35,P=0.222).
孕妇接受的预防性反药较少 (中位数为2比3),住院时间较长,尽管手术时间较短.

结论:

孕妇和非孕妇在接受非产科手术时表现出类似的PONV风险.
麻醉医生似乎对孕妇的预防性反药的使用较少.
进一步的研究可能是有必要的,以优化孕妇患者的PONV管理.

关键词:

抗药物抗药物抗药物整体麻醉是一种全身麻醉.引力引力引力引力手术后的恶心和吐.

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