宫弹性图:发现一种新的预测因子,可以改善在无并发双胞胎怀孕中预产早产的预测
Jinghua Li1, Shufa Yang2, Liying Zou3
1Department of Ultrasound, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, 100026, China.
Archives of gynecology and obstetrics
|June 27, 2023
概括
宫弹性声学,特别是CISmin,在预测双胞胎怀孕中早产方面表现有前途. 这种新的超声波技术可能比传统的方法 (如宫长度测量) 更准确.
科学领域:
- 产科和妇科 产科和妇科
- 医疗成像医学成像
- 周围生理学 周围生理学
背景情况:
- 双胞胎怀孕中的自发早产 (sPTB) 仍然是一个重大的临床挑战.
- 准确预测sPTB对于及时干预和改善新生儿结果至关重要.
- 像宫长度 (CL) 测量等传统方法在预测sPTB方面存在局限性.
研究的目的:
- 研究一种新的超声波参数 - - 宫弹性声学,用于在双胞胎怀孕中更好地预测sPTB.
- 为了比较弹性学参数的预测性能与传统的宫长度测量.
主要方法:
- 进行了一项涉及106例双胞胎怀孕的前性研究.
- 测量了宫弹性学参数,包括弹性对比指数 (ECI),宫硬度比率 (CHR),闭合的宫内部骨张力率 (CIS),外部宫骨张力率 (ES),以及它们的比率.
- 多变量后勤回归和Akaike信息标准 (AIC) 用于确定最佳预测指标,以及用于曲线下面面积 (AUC) 的接收器操作特征 (ROC) 曲线分析.
主要成果:
- 超过30%的参与者在怀孕35周之前分娩.
- 弹性学参数CISmin在预测35周前分娩方面表现出卓越的表现,显示最低的AIC和最高的AUC.
- CISmin显著优于传统的宫长度 (CLmin),它呈现了最高的AIC和最低的AUC.
结论:
- 宫弹性声学,特别是CISmin,与CL相比,可能是双胞胎怀孕中早产的更有效预测因素.
- 这种新的超声波方法可以增强临床决策,并改善双胞胎怀孕中sPTB的预测.
- 对宫弹性声学的进一步研究可能会导致临床实践在管理高风险怀孕方面取得重大进展.
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