什么是尾腺癌的适当的手术程序:尾切除术,部分切除术或右半切除术?
Bochao Zhao1, Zhicheng Ma2, Jingchao Wang2
1Department of Gastrointestinal Surgery, Tianjin First Central Hospital, No.24 Fukang Road, Nankai District, Tianjin, 300190, People's Republic of China. summerain2010@126.com.
概括
对于尾腺癌,尾切除术可能足以治疗第一阶段,但对于较晚的阶段,右侧尾切除术并不总是必要的. 适当的淋巴切除术对所有患者至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 在瘤学瘤学.
背景情况:
- 尾腺癌是一种罕见的恶性瘤.
- 手术管理策略各不相同,影响患者的治疗结果.
研究的目的:
- 为了确定尾腺癌的最佳手术程序.
- 为了指导临床决策,关于手术的范围.
主要方法:
- 从SEER数据库中对1984名尾腺癌患者 (2004-2015) 的回顾性分析.
- 在三个手术组中比较生存结果 (整体存活率,癌症特定存活率):尾切除术,部分切除术和右半切除术.
- 评估临床病理特征和预后因素.
主要成果:
- 与尾切除术相比,右侧半尾切除术改善了整体存活率 (OS) 和癌症特定存活率 (CSS) (P < .001).
- 右半球切除术和部分切除术之间没有显著的生存差异.
- 尾切除术对II期疾病的效果较差,而右侧半尾切除术对晚期疾病的部分尾切除术没有任何优势.
结论:
- 尾切除术可能足以治疗第一阶段尾腺癌.
- 对于高级阶段的右半球切除术并不总是优于部分切除术.
- 建议对所有患者进行适当的淋巴切除术,无论手术程度如何.
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