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Updated: Jul 25, 2025

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IKK通过抑制RIPK1-依赖性亡和激活NF-κBB来促进原始T细胞的存活

Fiona Carty1, Scott Layzell1, Alessandro Barbarulo1

  • 1Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London NW3 2PP, UK.

Science signaling
|June 27, 2023
PubMed
概括

克B激酶 (IKK) 抑制剂通过阻断细胞死亡途径和激活NF-κB来维持T细胞生存至关重要. 这种双重机制确保了原始CD4+T细胞的长期生存能力.

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