自我报告的克罗恩病治疗有效性,使用了新的众包网络平台
Tal Engel1,2, Eran Dotan2,3, Yossi Synett3
1Department of Gastroenterology, Sheba Medical Center, Ramat Gan, Israel.
United European gastroenterology journal
|June 28, 2023
概括
这项研究发现,Infliximab是克罗恩病最有效的治疗方法,基于来自人工智能支持的在线平台的患者报告的结果. 该平台帮助患者和医生选择最好的治疗方法来治疗克罗恩病.
科学领域:
- 数字健康数字健康
- 人工智能在医学中的应用
- 患者报告的结果
背景情况:
- 互联网平台使得慢性疾病患者体验数据的收集成为可能.
- StuffThatWorks (STW) 是一个针对慢性病患者的AI和众包平台.
- 这项研究重点关注克罗恩病患者报告的结局.
研究的目的:
- 开展一项国际,人工智能驱动,众包研究,研究患者报告的克罗恩病治疗有效性.
- 通过使用现实世界患者数据,分析和排名克罗恩病各种治疗方法的有效性.
- 评估在线平台对收集和分析患者报告结果的有用性.
主要方法:
- 使用专有STW贝叶斯推理模型来评估治疗的有效性.
- 对于克罗恩病的严重程度,有效性以1-5的比例进行测量.
- 对于一线生物治疗,计算了多次比较和几率比率.
主要成果:
- 7593名克罗恩病患者被纳入分析.
- 因弗利西马布被评为最有效的治疗方法,其次是肠道手术,阿达利穆马布,乌斯提金乌马布和维多利祖马布.
- 与vedolizumab相比,infliximab,adalimumab和ustekinumab显示出更高的有效性.
结论:
- 这是第一个众包人工智能平台对克罗恩病自我报告的治疗有效性的研究.
- 在线患者报告结果平台可以帮助临床医生和患者选择治疗.
- 众包数据为慢性疾病的实际治疗效果提供了宝贵的见解.
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