针对专门护理单位的基于规则的技术生成抗生素的缺陷
David M Hill1, Lorraine A Todor1
1Department of Pharmacy, Regional One Health, Memphis, TN 38103, USA.
Antibiotics (Basel, Switzerland)
|June 28, 2023
概括
自动化抗生素图表可能会误导病原体的易感性. 手动审查附加规则提供了更准确的图片,对于在烧伤中心有效选择抗生素至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
- 医疗信息学 医疗信息学
背景情况:
- 准确的抗生素图表对于指导抗生素治疗至关重要,特别是在高风险环境中,如烧伤中心.
- 自动化,基于规则的技术 (RBT) 抗生素图越来越多地使用,但可能无法捕获所有相关的临床细微差别.
- 使用增强规则的图表审查为更精确的抗生素图表生成提供了潜在的替代方案.
研究的目的:
- 为了比较自动RBT抗生素和手动衍生抗生素之间的病原体识别和抗菌敏感性模式,添加了规则.
- 评估将临床因素纳入烧伤患者抗生素图分析中的影响.
主要方法:
- 两年来从烧伤中心患者的细菌培养的回顾性队列研究.
- 对照RBT抗生素图与使用手动图表审查和额外的临床标准创建的新版本进行比较.
- 包括诸如入院后的几天,医院获得的风险因素和之前的抗生素疗程等因素.
主要成果:
- 在RBT和手工衍生抗生素图之间观察到病原体敏感性的显著差异.
- 包括临床因素改变了推的经验性格拉姆阴性抗生素治疗,从双重覆盖到单一,高度敏感的β-lactam.
- 在初始和随后的抗生素疗程之间,抗生素敏感性有显著的变化.
结论:
- 自动RBT抗生素图可能不能完全反映复杂患者群体中真正的病原体易感性.
- 手动查看图表,结合临床数据,提供更准确的抗生素图,从而优化了抗生素建议.
- 仔细考虑自动化标准对于解释抗生素图表至关重要,特别是在长期住院的病房.
关键词:
抗生素抗生素表 抗生素表抗微生物耐药性 抗微生物耐药性抗微生物药物管理管理人工智能的人工智能是人工智能.烧伤,烧伤,烧伤就是一个问题.关键护理关键护理的关键护理基于规则的技术 基于规则的技术创伤的创伤创伤的创伤.更多相关视频
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