大气氨对肉骨肌肉生长的影响
Xin Zhao1, Guangju Wang1, Hongyu Han1
1State Key Laboratory of Animals Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Animals : an open access journal from MDPI
|June 28, 2023
概括
在家禽养场中的高氨含量会对肉生长产生负面影响. 暴露于35ppm氨酸减少了骨肌肉的增长,可能是通过肌静止素途径.
科学领域:
- 禽畜科学 禽畜科学 禽畜科学
- 动物生理学 动物生理学
- 环境毒理学环境毒理学
背景情况:
- 氨是家禽的主要污染物,影响鸟类的健康和表现.
- 呼吸系统问题和生长减缓是已知的影响,但对骨肌肉的影响还未得到充分研究.
研究的目的:
- 调查慢性氨暴露对 brojler 骨肌肉生长和相关基因表达的影响.
- 为了确定潜在的分子机制背后的氨诱导增长抑制在 brojlers.
主要方法:
- 144只肉被暴露在0ppm或35ppm的氨中,持续了21天.
- 测量包括体重,肌肉体重,穿着体重和血清生物化学.
- 分析了骨肌纤维形态和基因表达 (肌素,肌素重链).
主要成果:
- 暴露于氨气显著降低肉的体重和肌肉发育 (乳房,大腿,穿着体重).
- 观察到血尿酸的增加和肌肉纤维直径的缩短.
- 肌素表达增加,而肌素重链基因表达减少.
结论:
- 35 ppm的大气氨显著影响肉的骨肌肉生长率.
- 肌静素通路是氨压力下肌肉纤维生长的潜在调节者.
相关概念视频
Overview of Protein Metabolism
1.4K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
1.4K
Urea Cycle
45.0K
The urea cycle describes how liver cells convert ammonia to urea. Ammonia is a toxic waste product of protein catabolism. Land animals must convert ammonia into the less toxic urea which can be safely eliminated by the kidneys through urine. Marine animals excrete ammonia directly, and the surrounding water dilutes the ammonia to safe levels.
45.0K
Overview of Nitrogen Metabolism
8.2K
Nitrogen is a very important element for life because it is a major constituent of proteins and nucleic acids. It is a macronutrient, and in nature, it is recycled from organic compounds and stored in the form of ammonia, ammonium ions, nitrate, nitrite, or nitrogen gas by many metabolic processes. Many of these metabolic processes are carried out only by prokaryotes.
The largest pool of nitrogen available in the terrestrial ecosystem is gaseous nitrogen (N2) from the air, but this...
The largest pool of nitrogen available in the terrestrial ecosystem is gaseous nitrogen (N2) from the air, but this...
8.2K
Comparative Excretory Systems
19.7K
Animals have evolved different strategies for excretion, the removal of waste from the body. Most waste must be dissolved in water to be excreted, so an animal’s excretory strategy directly affects its water balance.
19.7K
Inorganic Nitrogen Assimilation
49
Nitrogen is an essential element in biological systems, forming a crucial component of proteins, nucleic acids, and other cellular constituents. Many bacteria and archaea acquire nitrogen in the form of nitrate (NO₃⁻) or ammonia (NH₃), which are then assimilated into biomolecules through specific enzymatic pathways.Assimilatory Nitrate ReductionWhen nitrate enters the cell, it undergoes a two-step reduction process known as assimilatory nitrate reduction. Initially, the enzyme...
49
2° Amines to N-Nitrosamines: Reaction with NaNO2
4.3K
Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.
4.3K


