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Updated: Jul 25, 2025

Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies
06:33

Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies

Published on: November 10, 2023

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在KMT2A中,骨髓微环境诱导的化学保护被重组的儿科AML通过阿扎西丁-帕诺宾诺斯塔特组合克服

Kara M Lehner1,2, Anilkumar Gopalakrishnapillai1,2, Edward Anders Kolb1

  • 1Lisa Dean Moseley Foundation Institute for Cancer and Blood Disorders, Nemours Children's Hospital, Wilmington, DE 19803, USA.

Cancers
|June 28, 2023
PubMed
概括

新型表观遗传药物阿扎西提丁和帕诺比诺斯塔特在儿科急性髓性白血病 (AML) 中克服了骨髓保护. 这种组合使白血病细胞对化疗敏感,提高治疗疗效,并可能降低复发率.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.亚扎西提丁是一种阿扎西提丁.化学敏感性 化学敏感性共同培养是一种共同文化.表观遗传学是指表观遗传学.这是一个Panobinostat.儿科 儿科 儿科异种移植 异种移植 异种移植

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