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儿童,青少年和年轻成年人的含脂肪软组织瘤:哪些需要做活检?
Liesbeth Cardoen1, Nayla Nicolas1, Violette Le Gaudu1
1Department of Imaging, Institut Curie, 75005 Paris, France.
Cancers
|June 28, 2023
概括
大多数小儿脂肪含软组织瘤 (STT) 是良性的. 建议对10岁以上的儿童进行活检,这些儿童有先导性疾病或成像显示低脂肪 (<25%) 或myxoid区域.
科学领域:
- 儿科瘤学 儿科瘤学
- 放射学 放射学是一门学科.
- 病理学 病理学 病理学
背景情况:
- 含脂肪的软组织瘤 (STT) 在儿童中很常见.
- 区分良性和恶性性交感染对于适当的管理至关重要.
- 图像对这些病变的初步评估起着关键作用.
研究的目的:
- 在儿科队列中确认含脂肪性性传播感染的一般良性性质.
- 为了确定特定的临床和成像特征,表明需要活检.
主要方法:
- 对患有脂肪性性传染病的儿科患者 (25岁以下) 的回顾性研究.
- 图像特征 (US,CT,MRI) 与组织病理学的相关性.
- 对临床数据的分析,包括年龄和易感条件.
主要成果:
- 分析了63种含脂肪的瘤;92%是良性的 (脂质母细胞瘤,脂质瘤,FHI等). ) 的情况.
- 5%的病例是脂肪肉瘤.
- 恶性与年龄>10岁相关,癌症倾向性状况,脂肪含量<25%,以及成像中的myxoid区域.
结论:
- 大多数含脂肪的儿科性传播疾病是良性的,可以通过临床和成像评估来诊断.
- 活检的指示可以改进到老年儿童 (>10岁) 具有特定的风险因素或可疑的成像发现.
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