法医年龄估计:在回顾性人口研究中的多因素方法
Monika Bjelopavlovic1, Sebastian R Reder2, Isabel Fritzen1
1Department of Prosthetic Dentistry, University Medical Center, Johannes Gutenberg University Mainz, Augustusplatz 2, 55131 Mainz, Germany.
Diagnostics (Basel, Switzerland)
|June 28, 2023
概括
在德国人中,法医年龄估计的准确性通过将智慧牙和关节骨评估结合起来,使用圆束计算断层扫描 (CT) 来提高. 这种方法提高了生物年龄预测的可靠性.
科学领域:
- 法医人类学 法医人类学
- 放射学 放射学是一门学科.
- 牙科 牙科 牙科 牙科
背景情况:
- 准确的法医年龄估计对于法律和人类学的目的至关重要.
- 圆束计算机断层扫描 (CT) 为骨和牙分析提供了详细的成像.
- 之前的研究已经探索了个别的骨和牙指标,以评估年龄.
研究的目的:
- 评估结合关节骨和智牙评估的准确性,以在德国人口中进行法医年龄估计.
- 为了确定形光束CT数据在预测生物年龄方面的可靠性.
- 为了比较单个指标与组合模型的预测能力.
主要方法:
- 161个已知年龄的个体的形光束CT数据集由三个评分员分析.
- 关节骨骨化分阶段进行 (1-5),用德米尔吉安方法对智进行分类.
- 类间相关性 (ICC) 评估评级者协议;回归模型预测时间年龄.
主要成果:
- 观察到高的评价者间一致性 (ICCs 0.82-0.88).
- 线性估计高估了年龄,特别是对于18岁以上的人来说,关节骨显示了最高的高估.
- 结合关节骨和智牙数据,显著改善了年龄预测 (智牙的R2增加了14-15%).
结论:
- 使用CT进行的法医年龄估计通过将智慧牙分析与关节骨评估相结合而显著增强.
- 与单个指标相比,组合的多指标模型提供了更高的预测准确性.
- 这种方法为在法医背景下确定生物年龄提供了更可靠的方法.
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