多发性硬化症相关的饮食和营养问题:更新的范围审查,重点关注儿科
Claudia Mandato1, Angelo Colucci1, Roberta Lanzillo2
1Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", Pediatrics Section, University of Salerno, 84081 Baronissi, Salerno, Italy.
Children (Basel, Switzerland)
|June 28, 2023
概括
富含水果,蔬菜和全谷物的均衡饮食,同时限制加工食品,有助于肠道健康,并可能改善多发性硬化症 (MS) 的结果. 保持体力活动也被建议用于MS的预防和管理.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
背景情况:
- 生活方式和饮食显著影响多发性硬化症 (MS) 的发展和进展.
- 多发性硬化症涉及肠道和大脑屏障的修改,影响肠-大脑轴 (GBA).
研究的目的:
- 为了检查肠-大脑屏障变化的病理机制在MS.
- 审查饮食干预措施和补充剂,以改善所有年龄组的MS结果.
主要方法:
- 进行了范围范围的文献搜索.
- 对MS相关的GBA病理生理学和营养的基于证据的发现,在所有年龄段进行了分析.
主要成果:
- 对于MS来说,没有单一的"最佳"饮食;然而,均衡的饮食对于营养摄入至关重要.
- 富含水果,蔬菜,全谷物和瘦蛋白质的饮食,以及有限的加工食品,糖和和脂肪,显示出好处.
- 这些饮食具有抗氧化和抗炎性质,促进肠道微生物群,支持肠道和大脑屏障的完整性.
- 肥胖可能会加剧MS的发病和进展,特别是在儿科病例中.
- 维生素D和多不和脂肪酸是研究减少MS相关炎症的关键补充剂.
结论:
- 建议准确的饮食咨询和体育活动用于MS预防和管理.
- 进一步研究GBA向干预措施,如益生菌,益生菌和便微生物群移植正在进行中.
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