在Phelan-McDermid综合征中对感官处理进行未来一年的随访
Sergio Serrada-Tejeda1, Patricia Sánchez-Herrera-Baeza1, Rosa M Martínez-Piédrola1
1Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Rey Juan Carlos University, Avenida de Atenas s/n, CP 28922 Alcorcón, Spain.
Children (Basel, Switzerland)
|June 28, 2023
概括
费兰-麦克德米德综合征 (PMS) 与自闭症谱系障碍 (ASD) 有关. 一年的随访显示了触觉过敏反应的显著变化,影响了PMS患者的感觉处理.
科学领域:
- 遗传学 遗传学 是一个
- 神经发育障碍 神经发育障碍
- 感官处理 感官处理
背景情况:
- 费兰-麦克德米德综合征 (PMS) 是由染色体22的22q13.3缺失导致的.
- PMS是自闭症谱系障碍 (ASD) 的常见遗传原因.
- 在患有PMS的个体中,偶尔会注意到感官反应性困难.
研究的目的:
- 在患有PMS的个体中,研究一年内感官反应能力的变化.
- 评估44名PMS参与者队列中感官处理的纵向演变.
主要方法:
- 利用短感官概况 (SSP) 来评估感官反应性.
- 采用双因素ANOVA与重复测量来分析得分变化.
- 基线感官反应性得分与一年后的随访结果进行了比较.
主要成果:
- 一年后观察到触觉过敏反应的显著变化 (p = 0.003).
- 其他感官反应性变量,包括低响应性和感官寻找,没有显著变化.
- 听觉过的困难和低/弱能量水平被注意到.
结论:
- 了解感官反应的进展对于管理PMS行为调整至关重要.
- 可以制定有针对性的干预措施,以解决PMS患者的特定感官反应性挑战.
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