表明维生素D和勃起功能障碍之间存在关系的机制:概述
Andrea Crafa1, Rossella Cannarella1,2, Federica Barbagallo1
1Department of Clinical and Experimental Medicine, University of Catania, 95121 Catania, Italy.
Biomolecules
|June 28, 2023
概括
维生素D缺乏 (VDD) 与男性勃起功能障碍 (ED) 有关. 通过补充剂解决VDD可能会改善勃起功能,但需要更多的研究.
科学领域:
- 内分泌学 在内分泌学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 心血管健康 心血管健康
背景情况:
- 维生素D缺乏 (VDD) 和勃起功能障碍 (ED) 在老年男性中很普遍.
- 新出现的证据表明,通过各种生理机制,VDD和ED之间存在潜在联系.
研究的目的:
- 审查证据和机制,将维生素D水平与勃起功能联系起来.
- 总结关于维生素D和ED之间的关联的元分析数据.
- 为了突出进一步研究的需要,由于目前研究的局限性.
主要方法:
- 在体外,动物和人类研究的全面审查.
- 对将维生素D与内皮功能和ED联系起来的机制的分析.
- 关于VDD和ED的元分析证据的摘要.
主要成果:
- 低维生素D水平可能会通过多种途径导致勃起功能恶化.
- 维生素D通过炎症,氧化应激,血管硬和氧化生产来影响内皮功能.
- 维生素D可以通过减轻相关的并发症,如高血压和糖尿病来影响ED.
结论:
- 低维生素D水平与勃起功能障碍有关.
- 建议在ED患者中测量维生素D,并在缺乏时补充.
- 需要进一步的高质量,异质的临床试验来证实维生素D补充剂对ED的有效性.
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