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预测下尿道,性和肠道功能,以及脊髓损伤后的自主反射障碍
Chiara Pavese1,2, Thomas M Kessler3
1Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
预测脊髓损伤 (SCI) 后的结果对于患者的康复至关重要. 本综述检查了膀,肠道和性功能以及自主反射障碍的现有模型,突出了研究需求.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 脊髓损伤 (SCI) 损害了控制重要功能的神经通路.
- 恢复下泌尿道,性和肠道功能是患者的优先事项.
- SCI增加了自主反射障碍的风险,这是一种危及生命的疾病.
研究的目的:
- 审查SCI后下游泌尿道,性和肠道功能的当前知识和预测模型.
- 评估现有的模型来预测SCI后的自主反射障碍.
- 确定研究重点,以改善SCI中的功能性结果预测.
主要方法:
- 对SCI功能结果预测现有文献的系统审查.
- 对可用的算法和风险因素进行批判性分析,以预测膀,肠道,性功能和自主反射障碍.
- 评估当前预测模型的可靠性和适用性.
主要成果:
- 在创伤和缺血性SCI后,对于下泌尿道和肠道功能存在可靠的预测算法.
- 已经确定了自主反射障碍的有限风险因素,但缺乏预测模型.
- 对于SCI后性功能演变的预测模型存在重大需求.
结论:
- 虽然在预测膀和肠道功能方面取得了进展,但在性功能和自主反射障碍方面仍然存在重大差距.
- 改进的预测模型对于个性化的患者咨询,康复和临床试验设计至关重要.
- 迫切需要进一步的研究,以开发强大的预测工具,用于SCI后所有受影响的功能.
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