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橄橄的生物活性化合物在呼吸系统疾病中的作用
Ubashini Vijakumaran1, Neng-Yao Goh1, Rabiatul Adawiyah Razali1
1Centre for Tissue Engineering & Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Cheras, Kuala Lumpur 56000, Malaysia.
Antioxidants (Basel, Switzerland)
|June 28, 2023
概括
橄的生物活性化合物为呼吸系统疾病提供抗氧化,抗炎和抗病毒的好处. 本综述探讨了它们在通过减少炎症和氧化应激来防御和治疗呼吸道感染方面的潜力.
科学领域:
- 营养药品和植物化学
- 呼吸系统医学 呼吸系统医学
- 传染性疾病 传染性疾病
背景情况:
- 呼吸道疾病是全球主要的死亡原因之一,COVID-19等新出现的感染加剧了这种情况.
- 炎症和氧化应激是呼吸系统疾病病理学的核心因素.
- 来自植物的化合物,例如来自橄的化合物,具有公认的营养药和治疗性质.
研究的目的:
- 审查橄橄生物活性化合物的抗氧化,抗炎和抗病毒特性,与呼吸系统疾病相关.
- 阐明橄化合物对呼吸系统的保护作用背后的分子机制.
- 为了解决对橄化合物的临床应用在呼吸道感染方面的有限理解.
主要方法:
- 文献综述侧重于研究研究橄油生物活性化合物的研究.
- 对这些化合物对抗炎症和氧化应激的分子作用的研究分析.
- 在呼吸道病原体的背景下探索它们的抗病毒潜力.
主要成果:
- 橄的生物活性化合物表现出显著的抗氧化,抗炎和抗病毒活性.
- 这些化合物主要通过减轻促炎细胞因子和氧化应激来产生保护作用.
- 有证据表明,对呼吸系统的防御和治疗有潜在的益处.
结论:
- 橄的生物活性化合物作为呼吸系统疾病的治疗策略具有前景.
- 对剂量,生物可用性和临床疗效的进一步研究是有必要的.
- 针对炎症和氧化应激路径是它们有益作用的关键机制.
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