月经周期的月经周期子阶段以显著降低心率变化率为标志
Ajna Hamidovic1, John Davis2, Margaret Wardle3
1Department of Pharmacy, University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612, USA.
Biology
|June 28, 2023
概括
高频率心率变化 (HF-HRV) 在排卵前显著下降. 孕激素在月经周期中不同地影响HF-HRV,影响心血管健康洞察力.
科学领域:
- 身体生理学 身体生理学
- 心血管健康 心血管健康
- 生殖内分泌学 生殖内分泌学
背景情况:
- 高频心率变化 (HF-HRV) 是一个关键的超日节律,反映了副交感神经系统 (PNS) 活动.
- 在月经周期 (MC) 中HF-HRV的变化和孕激素的潜在调解仍然在很大程度上未被探索.
- 鉴于女性心血管疾病死亡率较高,了解这些波动至关重要.
研究的目的:
- 为了研究整个月经周期中HF-HRV如何变化.
- 为了确定孕激素水平是否与不同月经周期阶段的高频率-高频率变化相关.
- 为了确定与显著的高频率-高频率变化相关的特定月经周期阶段.
主要方法:
- 招募了33名女性,在他们的MC中进行了8次诊所访问.
- 测量休息HF-HRV并采集血清样本用于素激素 (LH) 和孕激素分析.
- 将数据重新调整为LH激增,定义早期的卵泡,中期的卵泡,周排卵期,早期的白色卵泡,中期的白色卵泡和晚期的白色卵泡子相.
主要成果:
- 在早期卵泡和周排卵阶段之间观察到HF-HRV的显著差异 (p ≤ 0.001).
- 在周排卵期和早期黄质期之间,观察到HF-HRV的显著下降 (p ≤0.05).
- 孕激素在早期的卵泡阶段与高频率-高频率-高频率呈阳性关联,但在周排卵阶段没有 (p ≤0.05).
结论:
- 高频频-高频频经历了预期排卵的显著下降.
- 孕激素与HF-HRV的关联在每个月经周期阶段都不同.
- 进一步的研究是必要的,以了解这些高频-高频动态在妇女中,特别是关于心血管健康.
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