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两鱼的水上鱼类中的多种适应性进化实例
Héctor Lorente-Martínez1, Ainhoa Agorreta1, Iker Irisarri2
1Department of Biodiversity, Ecology, and Evolution, Faculty of Biological Sciences, Complutense University of Madrid, 28040 Madrid, Spain.
Biology
|June 28, 2023
概括
水素 (AQP) 对于透调节至关重要. 这项研究揭示了两鱼类5个类中的21个AQP的适应性进化,AQP11显示了显著的变化,可能有助于从水到陆的过渡.
科学领域:
- 进化生物学是进化的生物学.
- 分子生物学分子生物学
- 生理学 生理学 生理学
背景情况:
- 水蛋白 (AQP) 是对透调节至关重要的跨膜蛋白.
- 它们在四足动物陆地殖民中的作用已知,但它们在两鱼向陆地过渡中的功能尚不清楚.
研究的目的:
- 为了研究22种两行动类鱼类物种中AQP的分子进化.
- 为了确定AQP基因家族动态,适应性进化和与两动物生活方式相关的结构变化.
主要方法:
- 汇集了22种两鱼类的AQP综合数据集.
- 列出了AQP的类别和类别,分析了基因家族的出生/死亡过程.
- 通过植物遗传学方法和重建的蛋白质模型测试了积极选择.
主要成果:
- 在5个类别的21个AQP中确定了适应性进化.
- 在AQP11类中发现了显著的积极选择,影响了许多分支和蛋白质位点.
- 检测到的序列变化表明功能和结构修改可能与两动物适应有关.
结论:
- 水素AQP11的正方体是促进两鱼从水到陆的过渡的关键候选物.
- AQP的适应性进化,特别是AQP11,可能在两生活方式的获得中发挥了作用.
- 在Gobiidae分类中的AQP11b的积极选择表明了土地适应的潜在扩散.
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