新兴的拉布多病毒和人类感染
James G Shepherd1, Chris Davis1, Daniel G Streicker1,2
1Centre for Virus Research, MRC-University of Glasgow, Glasgow G61 1QH, UK.
Biology
|June 28, 2023
概括
这篇综述强调了除了导致人类疾病的狂犬病 lyssavirus之外的rhabdoviruses. 进一步的研究对于理解和管理这些新出现的传染病至关重要.
科学领域:
- 病毒学 病毒学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 拉布多维病毒 (Rhabdoviridae) 是一个多样化的病毒家族,其成员感染脊椎动物,关节动物和植物.
- 狂犬病lyssavirus是人类的主要病原体,导致狂犬病,一种被忽视的疾病.
- 在人类发烧性疾病中,越来越多地发现了新型和很少检测到的rhabdoviruses.
研究的目的:
- 审查与人类感染相关的狂犬病病毒,不包括狂犬病 lyssavirus.
- 讨论在人类群体中发现和重新出现特定的拉布多病毒.
- 强调需要对这些研究不足的病毒进行进一步研究.
主要方法:
- 关于导致人类感染的拉布多病毒的文献综述.
- 在临床样本中分析下一代测序的发现.
- 讨论病毒发现,重新出现和地理分布.
主要成果:
- 在人体样本中发现了几种新型或很少检测到的rhabdovirus,通常在低收入和中等收入国家.
- 像巴斯刚果病毒,Ekpoma病毒,Le Dantec病毒和Chandipura病毒这样的病毒与人类疾病有关.
- 像Le Dantec病毒这样的病毒的重新出现凸显了持续的传播风险.
结论:
- 除狂犬病 lyssavirus 之外,其他的狂犬病病毒对人类健康构成重大,但未经定量化的威胁.
- 优先研究这些病毒对于疾病控制和预防至关重要.
- 了解这些狂犬病病毒的流行病学和临床影响对于公共卫生倡议至关重要.
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