糖尿病和高血糖症对水平引导骨再生的影响:临床前景分析
Paolo De Angelis1, Edoardo Rella1, Paolo Francesco Manicone1
1Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS-Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Healthcare (Basel, Switzerland)
|June 28, 2023
概括
患有控制糖尿病 (HbA1c < 7%) 的患者可以通过指导骨再生 (GBR) 实现成功的水平骨收益. 这种程序是有效的治疗缩膜脊,即使在不同的血糖控制水平.
科学领域:
- 在口腔外科手术中.
- 牙周病学 牙周病学
- 复原牙科是复原牙科的一种.
背景情况:
- 缩性气膜脊对牙植入物放置构成挑战.
- 指导骨再生 (GBR) 是骨重建的一个关键技术.
- 血糖控制是手术结果的一个关键因素.
研究的目的:
- 评估血糖控制与水平GBR结果之间的关系.
- 为了评估在GBR之后的水平和垂直骨尺寸变化.
- 为了确定不同HbA1c水平的患者的植入成功率.
主要方法:
- 对接受横 GBR 的患者的回顾性分析.
- 根据HbA1c水平将患者分为三组.
- 在手术后6个月测量膜脊的尺寸变化.
主要成果:
- 在所有组中观察到高植入成功率 (95.8%).
- 在正常血糖和高血糖/糖尿病组之间,水平骨增长的统计学上显著差异.
- 患有HbA1c<7%的患者实现了显著的水平骨增长.
结论:
- 控制的糖尿病 (HbA1c < 7%) 并不能排除成功的水平GBR.
- 在受控糖尿病患者中,GBR是一种可行的选择,用于膜脊增大.
- 血糖控制是GBR结果的一个重要考虑因素.
更多相关视频
02:08Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
Published on: July 5, 2024
832
09:34Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair
Published on: September 7, 2017
9.3K
相关概念视频
Hypoglycemia and Glucagon
306
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
306
Hormones Regulating Blood Glucose
3.6K
Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...
In addition to accelerating glucose uptake and utilization, insulin has...
3.6K
