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Updated: Jul 25, 2025

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

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德诺苏马布通过减弱RANK/RANKL信号来减轻葡萄糖脂毒性诱导的β细胞功能障碍和细胞亡

Sheng-Chieh Lin1,2, Sing-Hua Tsou3, Chien-Yin Kuo1,4

  • 1Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.

International journal of molecular sciences
|June 28, 2023
PubMed
概括

代诺苏马布 (DMB) 通过阻断RANK/RANKL通路,保护胰腺β细胞免受2型糖尿病的葡萄糖脂毒性影响. 这保护了β细胞的功能和生存,提供了潜在的治疗策略.

关键词:
在RANK/RANKL路径中.这里没有denosumab.葡萄糖脂质毒性 葡萄糖脂质毒性胰腺β细胞是什么2 型糖尿病 2 型糖尿病

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