首页 脉压力预测腹腔透析患者的死亡和心血管事件
Vincenzo Panuccio1, Pasquale Fabio Provenzano2, Rocco Tripepi2
1Nephology, Dialysis and Transplantation Unit-GOM "Bianchi-Melacrino-Morelli", Via Vallone Petrara SNC, 89124 Reggio Calabria, Italy.
Journal of clinical medicine
|June 28, 2023
概括
家庭脉压是腹腔透析 (PD) 患者死亡率的重要预测因素. 较高的家庭脉压 (HPP) 与增加的死亡风险有关,这突出了其在治疗PD患者中的重要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 临床医学 临床医学
背景情况:
- 动脉高血压在腹腔透析 (PD) 患者中很常见,通常与流体过载有关.
- 脉压预测透析患者的死亡率,但其在PD中的作用尚不清楚.
研究的目的:
- 为了研究家庭脉冲压 (HPP) 与PD患者的存活率之间的关联.
- 确定HPP是否是该人口中死亡率的独立预测因素.
主要方法:
- 140名PD患者的队列被跟踪平均35个月.
- 使用考克斯回归分析来评估HPP与死亡率之间的关系,并根据相关的共变量进行调整.
主要成果:
- 在HPP中增加5个单位与17%的死亡风险增加有关 (HR 1.17).
- 在调整年龄,性别,糖尿病,缩血压和透析充足度 (HR 1.31) 之后,这种关联仍然显著.
- 对于死亡或心血管事件的结合终点观察到类似的结果.
结论:
- 家庭脉压是PD患者全因死亡率的强有力的预测指标.
- 测量HPP是一种可行的方法来识别高风险PD患者.
- 最佳的血压控制和监测心血管风险指标,如HPP对于管理PD患者至关重要.
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