相关实验视频

Updated: Jul 25, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

挑战在患者中白血细胞计数的解释毒症随着包装细胞输血后的患者

Moti Klein^1,2, Lior Hassan^2,3, Rivka Katz²

¹General Intensive Care Unit, Soroka University Medical Center, and The Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 7747629, Israel.

Journal of clinical medicine

|June 28, 2023

概括

危急性败血症患者的包装细胞输血 (PCT) 只会对白细胞 (WBC) 数量造成轻微变化. 这项研究发现PCT后对WBC水平的临床影响最小.

科学领域:

关键护理医学关键护理医学
血液学血液学血液学

背景情况:

败血症是一种危及生命的疾病,需要重症监护.
包装细胞输血 (PCT) 是常见的严重病症败血症患者.
PCT对白细胞 (WBC) 计数的潜在影响需要调查.

研究的目的:

为了研究PCT对WBC数量的影响,在患有败血症的重症患者中.
为了量化PCT管理后白细胞计数的变化.

主要方法:

基于人口的回顾性队列研究.
包括962名接受PCT一单元的患者和994名匹配的对照.
分析的白细胞计数在PCT前后24小时使用混合线性回归.

主要成果:

在24小时内,PCT和非PCT组的白细胞计数均下降.
在PCT组中,白细胞计数的减少略显于PCT组.
在PCT后观察到白细胞计数平均下降0.45 × 10^9/L.
在PCT前的WBC水平预测PCT后的WBC水平.

结论:

在重症败血症患者中,PCT的使用会导致白细胞计数的轻微,临床上无意义的变化.
这些发现表明,PCT在这个患者群体中不会显著改变WBC动态.

关键词:

感染的感染感染.重症监护病房的重症监护病房是一个重症监护病房.血清细胞形成的白细胞症.这是一种血症.白血细胞的数量可以计数.

更多相关视频

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

相关概念视频

Structure and Function of Leukocytes

Structure and Function of Leukocytes

An adult in good health typically has between 4,500 and 11,000 leukocytes, or white blood cells, per microliter of blood, which constitutes about 1% of the total blood volume. Unlike red blood cells, white blood cells contain a nucleus and other cellular organelles but do not have hemoglobin. Most white blood cells reside in connective tissues, particularly in lymphatic organs such as the lymph nodes, with only a small fraction present in circulating blood.
White blood cells protect the body...

Disorders of Leukocytes

Disorders of Leukocytes

Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...