四个分期分类的比较性能,以选择"高风险"的头部和部皮肤状细胞癌
Roxane Elaldi1,2, Emmanuel Chamorey3, Renaud Schiappa3
1Face and Neck Surgery Department, Antoine Lacassagne Center, 06100 Nice, France.
Journal of clinical medicine
|June 28, 2023
概括
与其他系统相比,布里格姆和妇女医院 (BWH) 的分类证明了在识别高风险头皮状细胞癌 (HNCSCC) 方面具有优越的特异性和积极的预测价值.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 手术瘤学手术瘤学
背景情况:
- 头部和部皮肤状细胞癌 (HNCSCC) 的管理依赖于准确的风险分层.
- 现有的高风险HNCSCC分类系统在预测能力上有所不同.
研究的目的:
- 为了比较布里格姆和妇女医院 (BWH) 分类与既有系统的性能.
- 评估BWH分类在预测HNCSCC患者不良结果方面的有效性.
主要方法:
- 从单一的三级保健中心对217例HNCSCC病例进行了回顾性分析.
- 使用BWH,AJCC8,UICC8和NCCN标准将瘤分类为低风险或高风险.
- 评估局部复发,淋巴结复发和疾病特异性死亡率.
主要成果:
- 血淋病分类表现出最高的特异性和积极的预测价值,用于预测不良结果和淋巴结复发.
- 对于BWH,一致性指数与AJCC8和UICC8相当,但优于NCCN.
- 国家综合癌症网络 (NCCN) 分类表现出最少的歧视力.
结论:
- 在HNCSCC中,BWH分类似乎最适合预测HNCSCC的不良结果.
- 这一发现支持BWH系统在指导高风险HNCSCC的临床决策方面的实用性.
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