越南COPD患有喘特征的患者:患病率和适合个性化医疗的适用性
Nguyen Van Tho1,2, Thu Phuong Phan3,4, Anh Tuan Dinh-Xuan5
1Department of Tuberculosis and Lung Diseases, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Journal of personalized medicine
|June 28, 2023
概括
越南有很大比例的COPD患者表现出喘特征,通常年轻,肺功能更好. 这些患者经常受益于吸入性皮质类固醇/长效β-2激动剂治疗.
科学领域:
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
- 临床流行病学临床流行病学
背景情况:
- 慢性阻塞性肺病 (COPD) 管理通常涉及吸入性皮质类固醇 (ICS) 对于患有喘特征的患者.
- 具有喘特征的COPD患者的患病率和临床特征需要进一步调查,特别是在不同的地理区域.
研究的目的:
- 确定越南COPD患者中喘特征的比例.
- 为了比较COPD患者与没有喘特征之间的临床特征和当前药物使用情况.
主要方法:
- 在两个越南呼吸外科诊所进行了一项横截面研究.
- 医生根据GINA/GOLD指南确定了COPD患者的喘特征.
- 招募了300名患者,并收集了人口统计,肺功能和药物的数据.
主要成果:
- 在研究人群中,COPD患者患有喘特征的患病率为27.3%.
- 这些患者年轻,FEV1值较高,支气管扩展剂可逆性更强.
- 在患有喘特征的慢性肺炎患者中,观察到血中乙氨基酸细胞数量增加和ICS/长效支气管扩展剂β-2激动剂 (LABA) 的使用增加.
结论:
- 在越南,COPD与喘特征的高患病率需要量身定制的临床行动计划.
- 在COPD患者中识别喘特征可以指导治疗策略,有可能改善ICS/LABA疗法的结果.
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