中耳中的SARS-CoV-2-CovEar:一个潜在的试点研究
Nina Rubicz1,2, Nikolaus Poier-Fabian1,2, Christian Paar3
1Department of Otorhinolaryngology, Head and Neck Surgery, Kepler University Hospital GmbH, Krankenhausstrasse 9, 4020 Linz, Austria.
Journal of personalized medicine
|June 28, 2023
概括
在活着的患者中,SARS-CoV-2可以感染中耳,包括无症状的个体. 这一发现对耳部外科手术的安全性和潜在的音频垂体效应有影响.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病毒学 病毒学
- 传染性疾病 传染性疾病
背景情况:
- 尸检研究在中耳中检测到SARS-CoV-2,但其在活着的患者中的存在仍然不清楚.
- SARS-CoV-2向中耳的传播途径 (死后和感染期间) 尚未确定.
研究的目的:
- 在接受耳部手术的活生生的患者中耳中检测SARS-CoV-2的存在.
- 为了确定SARS-CoV-2是否可以在活体感染期间或活体感染后在中耳中检测到.
主要方法:
- 在耳部手术期间从鼻和中耳分泌物中收集的手术拭子.
- 使用聚合酶链反应 (PCR) 测试SARS-CoV-2的样本.
- 记录了患者数据,包括疫苗接种史,COVID-19状态和SARS-CoV-2暴露.
主要成果:
- 在两名参与者的中耳和四名参与者的鼻中检测到SARS-CoV-2.
- 在所有测试的情况下,气管过器仍然是无菌的.
- 在现存患者的中耳中发现了SARS-CoV-2,包括无症状个体.
结论:
- 在活着的患者中,SARS-CoV-2可以穿透中耳.
- 中耳中的SARS-CoV-2存在在耳部手术和手术室工作人员的风险.
- 中耳SARS-CoV-2感染可能会直接影响音频前庭系统.
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