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种族问题和炎症性肠道疾病的差异:我们可以从以色列阿拉伯人口身上学到什么?
Naim Abu-Freha1,2, Nour Ealiwa2, Muhammad AbuTailakh3,4
1The Institute of Gastroenterology and Hepatology, Soroka University Medical Center, Beer-Sheva 84101, Israel.
Journal of personalized medicine
|June 28, 2023
概括
炎症性肠道疾病 (IBD) 在同一医疗保健系统内的阿拉伯和犹太人口中呈现不同. 克罗恩病的阿拉伯患者在诊断时年轻,并有不同的并发症和并发症.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 临床医学 临床医学
背景情况:
- 炎症性肠道疾病 (IBD),包括克罗恩病 (CD) 和性结肠炎 (UC),在不同种族群体中越来越普遍.
- 了解IBD的种族差异对于公平的医疗保健提供和管理至关重要.
研究的目的:
- 为了比较阿拉伯和犹太人口之间的IBD的临床特征,并发症,治疗和结果.
- 在一个共享的医疗保健系统中,识别疾病表现和管理的潜在差异.
主要方法:
- 一项回顾性队列研究包括2000年至2021年期间被诊断患有CD或UC的成年患者.
- 分析了人口统计,疾病特征,肠外表现,并发症,治疗和死亡率的数据.
- 在阿拉伯和犹太患者队列之间进行了CD和UC的统计比较.
主要成果:
- 阿拉伯CD患者的诊断年龄较小 (36.1岁对39.9岁),并表现出较高的裂率,周,红斑结节,糖尿病,肥胖,肝硬化和男性不孕症.
- 阿拉伯CD患者接受的阿扎西奥普林/默卡普托普林较少,但接受的类固醇较多;抗TNF治疗率相似.
- 阿拉伯患者中CD全因死亡率较低 (8.4%对10.2%).
结论:
- 在阿拉伯和犹太人口之间,IBD特征,并发症和治疗模式存在显著差异.
- 这些发现凸显了对IBD管理的文化敏感和定制方法的需要.
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