社会隔离:关于自主神经系统与炎症之间的危险联系的叙事审查
Costanza Scatà1, Angelica Carandina1,2, Alice Della Torre1,2
1Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
社会隔离通过激活同情神经系统而影响健康,导致炎症和心血管问题. 了解这些联系对于未来的太空任务和流行病至关重要.
科学领域:
- 神经科学是一个神经科学.
- 免疫学 免疫学 免疫学
- 心血管科学 心血管科学
背景情况:
- 社会孤立和孤独与增加的死亡率和发病率有关.
- 自主神经系统 (ANS) 可能会调解这些健康影响,正如在极端环境和流行病期间的研究表明的那样.
- 交感性ANS激活可能导致有害的长期健康后果.
研究的目的:
- 审查太空研究和关于社会隔离和ANS激活的COVID-19封锁洞察力.
- 专注于社会隔离对心血管功能障碍和免疫系统失衡的影响.
- 了解连接社会隔离,ANS和健康结果的病理生理机制.
主要方法:
- 现有文献的叙述性审查.
- 分析来自太空任务和太空类型的数据.
- 检查COVID-19流行病封锁期间的调查结果.
主要成果:
- 社会隔离激活了交感神经系统,促进了炎症和心血管反应.
- 短期的交感激活是适应性的,但慢性激活会导致情绪障碍,心血管疾病和免疫失调.
- 来自太空和流行病背景的证据支持ANS在调解隔离对健康影响方面的作用.
结论:
- 自主神经系统在社会隔离对健康的有害影响中起着关键作用.
- 了解这些机制对于开发针对长期航天,未来的流行病和人口老龄化的对策至关重要.
- 需要进一步的研究,以减轻与各种环境中的社会隔离相关的健康风险.
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