在患有过敏性肺炎的患者中,肺高血压和右心室功能障碍的预测因素
Natalia V Trushenko1,2, Olga A Suvorova1, Galina V Nekludova1,2
1Pulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), Healthcare Ministry of Russia, Trubetskaya St. 8, Build. 2, 119991 Moscow, Russia.
肺高血压 (PH) 影响了近一半的慢性过敏性肺炎 (HP) 患者,特别是那些有纤维性HP的患者. 早期识别PH预测因素,如CT纤维化症状,对于管理这种肺病并发症至关重要.
科学领域:
- 肺部医学 肺部医学
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
背景情况:
- 过敏性肺炎 (HP) 是一种由吸入的抗原引发的间歇性肺病 (ILD).
- 纤维化HP表型可以进展并导致肺高血压 (PH).
研究的目的:
- 为了确定慢性HP患者中PH的患病率.
- 在这个人群中确定PH的预测因素.
主要方法:
- 这是一项85名HP患者的长度观察研究.
- 使用临床检查,问卷,HRCT,血液气体分析,6-MWT,PFT和心声回声.
主要成果:
- 在48.2%的患者中发现了PH,主要是纤维化HP患者.
- PH患者年龄较大,症状较强,FVC/DLco比率较高.
- 关键的PH预测因素包括CT纤维化,手指俱乐部,FVC/DLco,6-MWT SpO2和心血管疾病.
结论:
- 在慢性HP,尤其是纤维性HP中,PH很常见.
- 早期发现PH预测因子对于及时诊断和管理至关重要.
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