无烟烟草 (马拉斯粉) 对心上脂肪厚度和心室再极化参数的影响
Kemal Göçer1, Bayram Öztürk2, Murat Kaniyolu1
1Department of Cardiology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras 46050, Turkey.
Medicina (Kaunas, Lithuania)
|June 28, 2023
概括
无烟烟草,特别是Maras粉 (MP),可能会通过影响心上脂肪厚度和改变Tp-e等复极化参数来增加心室节律失常的风险. 这项研究将MP用户与吸烟者和非烟草用户进行了比较.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 临床研究 临床研究
背景情况:
- 无烟烟草 (ST) 的使用是吸烟的越来越多的替代品,健康风险相当或更大.
- 使用ST与心律失常的发病有关,可能是通过影响心室再极化.
- 马拉斯粉 (MP) 是一种特定类型的ST,其对心血管的影响,特别是对复极化和心上脂肪的影响,尚未得到充分研究.
研究的目的:
- 调查马拉斯粉 (MP) 使用与心上脂肪厚度 (EFT) 之间的关系.
- 在MP用户中检查新的心室再极化参数.
- 为了比较MP使用者,吸烟者和健康的非烟草使用者之间的这些参数和EFT.
主要方法:
- 一项涉及289名男性参与者的比较研究:97名MP使用者,97名吸烟者和95名健康对照.
- 分析了心电图 (ECG) 的复极化参数 (QT,Tp-e,cTp-e,Tp-e/QT,Tp-e/cQT).
- 使用心声谱测量心上脂肪厚度 (EFT);使用统计模型来评估EFT的预测因素.
主要成果:
- 两组之间没有观察到年龄或体重指数的显著差异.
- 与其他组相比,MP使用者表现出较高的低密度脂蛋白水平.
- MP使用者显示Tp-e,cTp-e,Tp-e/QT和Tp-e/cQT间隔显著增加,表明心室复极变化. MP使用是增加EFT的显著预测因素.
结论:
- 马拉斯粉的使用与心室再极化参数的显著变化有关.
- 使用MP可能会通过增加心上脂肪厚度和影响复极化而导致心室失常的病原性.
- 这些发现强调了与这种特定形式的无烟烟草相关的潜在心脏风险.
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