具有抗菌性质的聚合物的制备和功能化 - - 审查最近的发展
Monika Parcheta1, Magdalena Sobiesiak1
1Department of Polymer Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sklodowska University in Lublin, Maria Curie-Skłodowskiej sq 3., 20 031 Lublin, Poland.
Materials (Basel, Switzerland)
|June 28, 2023
概括
抗微生物聚合物有效地从水中去除有害细菌. 功能化聚合物和与抗生素的协同组合为打击抗生素耐药性和保护公共健康提供了有前途的解决方案.
科学领域:
- 环境科学 环境科学
- 材料科学 材料科学 材料科学
- 聚合物化学 聚合物化学
背景情况:
- 抗生素耐药细菌对环境和公共健康构成重大威胁,特别是通过受污染的水和食物.
- 从饮用水和废水中有效去除细菌对于预防水传播疾病至关重要.
研究的目的:
- 审查水中的细菌去除的聚合物基策略的最新进展.
- 探索功能化聚合物和聚合物-抗生素协同作用的方法中的抗菌活性机制.
主要方法:
- 研究了细菌细胞和功能化聚合物表面 (例如,银纳米粒子,四级化合物) 之间的静电相互作用.
- 研究了聚合物的协同效应 (例如,奇托,聚氧甲,聚酸) 与抗生素相结合,用于向药物输送.
- 总结了在修改聚合物表面以增强抗微生物特性方面最近的成就.
主要成果:
- 用金属 (例如,AgNPs,QACs) 功能化的聚合物通过静电相互作用证明了有效的细菌去除.
- 聚合物和抗生素的协同组合能够精确地向药物,减轻过度使用和抗生素耐药性.
- 阴离子聚合物,精油聚合物和改性天然聚合物显示出有望去除有害细菌的可能性.
结论:
- 抗微生物聚合物是可行的生物制剂,由于其低毒性,成本效益,稳定性和高吸附能力.
- 聚合物的表面修饰是赋予强大的抗微生物特性的一个关键策略.
- 这些进展为控制水资源中的细菌污染提供了有效的解决方案.
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