微生物群-肠-大脑轴和自闭症谱系障碍之间的相互联系比较治疗选择:一个范围审查
Angelo Michele Inchingolo1, Assunta Patano1, Fabio Piras1
1Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.
Microorganisms
|June 28, 2023
概括
这项研究表明,肠道微生物群干预措施,如益生菌,益生菌,共生菌和便微生物群移植,可能有助于管理自闭症谱系障碍 (ASD) 症状. 这些疗法在ASD患者中显示出改善胃肠道和中枢神经系统问题的潜力.
科学领域:
- 神经科学是一个神经科学.
- 胃肠病学 胃肠病学
- 微生物学 微生物学
背景情况:
- 自闭症谱系障碍 (ASD) 涉及社交沟通缺陷和重复性行为,通常在一岁时出现.
- 自闭症经常与同时出现的疾病有关,包括胃肠道问题,,焦虑,睡眠障碍和免疫功能障碍.
- 了解肠-大脑轴对于解决自闭症多面性质至关重要.
研究的目的:
- 审查目前关于肠道微生物向干预自闭症谱系障碍疗效的文献.
- 评估益生菌,益生菌,共生菌和便微生物群移植对ASD相关症状的影响.
主要方法:
- 从2013年1月到2023年2月,在PubMed,Scopus和Web of Science进行了系统的文献搜索.
- 使用的关键词是"自闭症"和"微生物群".
- 在对2370多个初始结果进行严格选后,对18篇精选的英语文章进行了定性分析.
主要成果:
- 针对肠道微生物群的干预措施在管理ASD方面表现有前途.
- 益生菌,益生菌,共生菌,便微生物群移植和微生物群转移疗法被确定为潜在的治疗途径.
- 这些干预措施可以解决与ASD相关的胃肠道和中枢神经系统症状.
结论:
- 肠道微生物群调制代表了自闭症谱系障碍患者的可行治疗策略.
- 需要进一步的研究来优化这些干预措施,并确认它们在ASD管理中的长期益处.
- 针对肠道微生物群可以提供新的方法来缓解ASD的核心症状和相关并发症.
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