甲状腺和性菌 Coss. :矿物成分,营养价值,植物化学分析和皮肤学特性
Ismail Mahdi1, Nidal Fahsi1, Hassan Annaz1
1AgroBioSciences Department, College for Sustainable Agriculture and Environmental Science, Mohammed VI Polytechnic University, Ben Guerir 43150, Morocco.
Molecules (Basel, Switzerland)
|June 28, 2023
概括
甲状腺和,或Zaitra,表现出显著的抗氧化和抗菌性质. 这项研究验证了其传统医疗用途,突出了其开发新药和皮肤病剂的潜力.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 皮肤病学 皮肤病学
背景情况:
- 甲状腺和 (Zaitra) 传统上用于医学.
- 它的矿物质,营养和植物成分尚未完全表征.
- 皮肤学应用需要科学验证.
研究的目的:
- 分析T. satureioides的矿物成分,营养价值和植物成分.
- 评估T. satureioides提取物的抗氧化和抗微生物活性.
- 评估其化合物的皮肤学潜力,包括皮肤透性和敏感性.
主要方法:
- 矿物质分析,氨基酸分析和多和黄的量化.
- 液体染色学-双重质谱学 (LC-MS/MS) 用于二次代谢物识别.
- 在体外抗氧化和抗微生物测试 (P. aeruginosa抑制,生物膜减少,运动性测试) 和在皮肤透性/敏感性预测.
主要成果:
- 高和铁含量;丰富的必需氨基酸 (60.8%).
- 提取物含有大量的多 (118.17毫克GAE/g) 和黄 (32.32毫克奎尔/g),以及46个已识别的二次代谢物.
- 显示出强烈的抗氧化活性,抑制P. aeruginosa生长 (MIC=50 mg/mL),减少生物膜形成 (35.13%),运动能力受损 (56.94%),并显示出有利的皮肤透性,对33种化合物敏感性风险低.
结论:
- T. satureioides具有宝贵的营养和植物化学特征.
- 提取物表现出强大的抗氧化和抗菌作用,特别是对P. aeruginosa.
- 化合物显示出有前途的皮肤学潜力,支持传统用途,并建议在药物和化品开发中的应用.
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