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Updated: Jul 25, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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通过常规的希夫基反应合成,晶体结构,DFT和一些imine型化合物的抗癌活性:意外循环转化为氧化衍生物的一个例子

Jamal Lasri1, Naser E Eltayeb1, Saied M Soliman2

  • 1Department of Chemistry, Rabigh College of Science and Arts, King Abdulaziz University, P.O. Box 344, Jeddah 21589, Saudi Arabia.

Molecules (Basel, Switzerland)
|June 28, 2023
PubMed
概括

研究人员合成了新型的imine化合物和一种oxazine衍生物,评估了它们的抗癌潜力. 化合物1对HepG2和MCF-7细胞系表现出最显著的抗癌活性,显示出药物开发的前景.

关键词:
在 DFT 方面,它是最重要的.希尔什菲尔德 (Hirshfeld) 是一个著名的艺术家.这是一种抗癌药物.伊米内伊米内 伊米内伊米内分子间相互作用的分子间相互作用.这种药物是oxazine.

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