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Updated: Jul 25, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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新型三氨酸衍生物具有选择性为c-Jun N-终端激酶 (JNK) 3抑制剂

Igor A Schepetkin1, Oleksander S Karpenko2, Anastasia R Kovrizhina3

  • 1Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.

Molecules (Basel, Switzerland)
|June 28, 2023
PubMed
概括

研究人员开发了新型的三素-6-oxime类似物作为选择性c-Jun N-终端激酶3 (JNK3) 抑制剂. 这些化合物显示出治疗炎症性疾病和神经退行性疾病 (如阿尔茨海默氏症) 的潜力.

关键词:
这是一种抗炎药物.c-六月 N-终端酶分子对接的分子对接.核因子-κBB 的核因子.一个oxime的oxime是什么选择性激酶抑制剂选择性激酶抑制剂三三氨酸的使用方法

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